Benzodiazepine Conversion Calculator

Created by Łucja Zaborowska, MD, PhD candidate
Reviewed by Steven Wooding
Last updated: Nov 15, 2022

The benzodiazepine conversion calculator is an ultimate solution to any dosage problems you might encounter while switching from one drug of this type to another. 💊

We're going to present a definitive benzo conversion chart, benzodiazepines classification, and the details of every drug's mode of action. We'll also compare some of the most popular anxiolytic medicines (drugs reducing anxiety), their side effects, and their applications.

What are benzodiazepines?

Benzodiazepines are a group of drugs used for treating anxiety – they will also make you feel more relaxed, help you fall asleep faster and on top of that – they may combat a few kinds of seizures. 🧘

Benzodiazepines are a new generation of drugs that almost totally replaced the older type of anti-anxiety drugs, barbiturates.

Why are benzodiazepines so popular? – one may ask;
in comparison to barbiturates, they are:

  • Much safer;
  • Less toxic;
  • Overdose is less probable; and, most of all;
  • There's a specific antidote called flumazenil, which can reverse the effects of benzodiazepines within seconds (yes, just like in the movies!). ⛱️

What are other anxiolytic medications?

Benzodiazepines are not the only drugs used for anxiety – we usually start our treatment with medicines such as Benadryl, that have a milder effect and are not as addictive as benzodiazepines. Read more about Benadryl by visiting the benadryl calculator.

Different opioids such as morphine or tramadol can be also used for this purpose, although the patient will probably face a variety of different side effects, e.g., constipation.

If you're looking for additional help, some chronic pain drugs such as gabapentin, can be used off-label to treat anxiety. We may also administer beta-blockers and melatonin to alleviate some additional effects of anxiety, such as a rapid heart beat or insomnia. Calculate a specific melatonin dose needed for a given indication using the melatonin dosage calculator.

💡 Want to screen for generalized anxiety disorder (GAD) and its severity? The Omni GAD-7 calculator is here to help.

Benzodiazepine half-life & benzodiazepine classification

The list of benzodiazepines can be divided into 3 groups based on the duration of their action and the speed of the onset of action. Our benzo calculator uses the first mentioned and most popular option – duration.

The table below lets you compare the mode of action of all popular benzos; are you looking for a clonazepam vs. Xanax comparison? Well, the benzodiazepine conversion calculator has got your back!

Benzodiazepine

Onset of action

Duration

Alprazolam (Xanax)

30 min

6-20 h

Bromazepam (Lexotan)

30 min - 4 h

10-20 h

Chlordiazepoxide (Librium)

1.5 h

5-30 h

Clonazepam (Rivotril)

1 h

18-39 h

Clorazepate (Tranxene)

1 h

36-200 h

Diazepam (Valium)

30 min

20-50 h

Flurazepam (Dalmane)

1 h

12-100 h

Lorazepam (Ativan)

30-60 min

10-20 h

Midazolam IV (Versed)

1-3 min

2-4 h

Midazolam PO

10-20 min

20 min - 3 h

Oxazepam (Serax)

3 h

3-21 h

Quazepam (Doral)

20-45 min

25-100 h

Temazepam (Restoril)

30-60 min

10-20 h

Triazolam (Halcion)

30 min

1.6-5.5 h

Benzodiazepine equivalency table – benzo conversion chart

Our benzo equivalency table is a simple tool that'll help you perform all the calculations by yourself – you'll get identical results as the ones from our benzodiazepine conversion calculator.

  1. We compare each one of our benzodiazepines to alprazolam. If that's the drug you're taking, simply multiple your dose by the number that's present beside the name of the drug you want to switch to.

  2. If you're taking any other medication than alprazolam right now, divide your dose by the number present by your drug's name, and then multiply it by the number written by the name of the drug you'd like to switch to (take a look at the example at the bottom of the page ⤵️).

Here's our benzo conversion table:

Benzodiazepine

×

Benzodiazepine

×

Alprazolam (Xanax)

1

Lorazepam (Ativan)

2

Bromazepam (Lexotan)

6

Midazolam IV (Versed)

4

Chlordiazepoxide (Librium)

50

Midazolam PO

10

Clonazepam (Rivotril)

1

Oxazepam (Serax)

30

Clorazepate (Tranxene)

20

Quazepam (Doral)

40

Diazepam (Valium)

15

Temazepam (Restoril)

30

Flurazepam (Dalmane)

30

Triazolam (Halcion)

0.5

Let's practice it all with a small example:

  • 🔄Temazepam to Xanax conversion
  1. Let's use the table and find the conversion numbers corresponding to both of our drugs:

Temazepam (Restoril)

30

Alprazolam (Xanax)

1

💡 Take a closer look – our equivalent benzodiazepine calculator gives you both generic (pharmaceutical) and brand names of all the drugs!

  1. Let's calculate the actual benzodiazepine equivalent doses!

    Let's say that your temazepam dose is equal to 20 mg.

    • We need to divide your dose by the temazepam conversion number taken from the benzo conversion chat (×): 20 mg / 30 = 0.67

    • Then, we'll have to multiply our result by the conversion number present in the benzo conversion table for Xanax (alprazolam). 0.67 * 1 = 0.67 mg

And here we go, 0.67 mg is our final alprazolam (Xanax) dose! 🎉 Compare it to your result computed with our benzodiazepine conversion calculator. 😉

Łucja Zaborowska, MD, PhD candidate
💡 Enter the dose of your drug to receive all the conversions.
Short duration (approx. 2-7 h)
Bromazepam (Lexotan)
mg
Midazolam IV (Versed)
mg
Midazolam PO
mg
Oxazepam (Serax)
mg
Triazolam (Halcion)
mg
Intermediate duration (approx. 4-10 h)
Alprazolam (Xanax)
mg
Lorazepam (Ativan)
mg
Temazepam (Restoril)
mg
Long duration (approx. 11-20 h)
Chlordiazepoxide (Librium)
mg
Clonazepam (Rivotril)
mg
Clorazepate (Tranxene)
mg
Diazepam (Valium)
mg
Flurazepam (Dalmane)
mg
Quazepam (Doral)
mg
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