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Gupta Risk Calculator

Created by Dominika Śmiałek, MD, PhD candidate
Reviewed by Dominik Czernia, PhD and Jack Bowater
Based on research by
Gupta PK, Gupta H, Sundaram A, Kaushik M, Fang X, Miller WJ, Esterbrooks DJ, Hunter CB, Pipinos II, Johanning JM, Lynch TG, Forse RA, Mohiuddin SM, Mooss AN. Development and Validation of a Risk Calculator for Prediction of Cardiac Risk After Surgery; Circulation; July 2011
Last updated: Dec 15, 2023

Are you looking for a tool to assess a patient's risk of cardiac incident in the perioperative period? This Gupta risk calculator uses Gupta risk score to calculate a patient's risk of cardiac event. For more information on the mortality in patients after a non-ST elevation myocardial infarction or with unstable angina, use our TIMI score calculator.

The article below contains some information on the Gupta cardiac risk formula, Gupta score interpretation, and practical application of this Gupta perioperative risk calculator.

What is Gupta perioperative risk?

Gupta perioperative risk calculator serves as a tool for calculating a patient's risk of a cardiac event - defined here as Myocardial Infarction or Cardiac Arrest (MICA). It is based on a study by Gupta et al., "Development and Validation of a Risk Calculator for Prediction of Cardiac Risk After Surgery".

It applies to patients in the perioperative period, that is, during surgery or 30 days after it.

The tool considers the general well-being of the patient, their age, kidney function, and how difficult the surgery is. Interestingly, it does not take into account some myocardial infarction risk factors, such as LDL levels (easy to estimate with our LDL calculator) or smoking status, which are essential while using CVD risk calculator.

Gupta score in medical practice

Patients with a high score require additional monitoring during and after surgery. It may be an echocardiogram, stress testing, ECG (including ECG heart rate calculation), and a consultation with a cardiologist.

Gupta risk calculator

The formula for determining the risk of myocardial infarction or cardiac arrest is:

cardiac risk [%] = ex / (1 + ex),


x = age * 0.02 + status + asa + creatinine + type - 5.25,

so, x depends on five variables, the values for which are given in brackets below:

  1. Age in years, multiplied by 0.02
  2. Status of a patient:
    • Totally independent (0)
    • Partially dependent (0.65)
    • Totally independent (1.03)
  3. ASA Class
    • Class 1: healthy (-5.17)
    • Class 2: mild systemic disease (-3.29)
    • Class 3: severe systemic disease (-1.92)
    • Class 4: a severe systemic disease that puts a patient's life at risk of death (-0.95)
    • Class 5: moribund, not expected to survive without surgery (0)
  4. Creatinine levels
    • Normal (≤1.5 mg/dL, 133 µmol/L (0)
    • Elevated (>1.5 mg/dL, 133 µmol/L (0.61)
  5. Type of surgery
    • Hernia: ventral, inguinal, femoral, and other (0)
    • Anorectal: anus and rectum (-0.16)
    • Aortic (1.6)
    • Bariatric (-0.25)
    • Brain (1.4)
    • Breast (-1.61)
    • Cardiac: Heart (1.01)
    • ENT, except thyroid and parathyroid (0.71)
    • Foregut/hepato-pancreaticobiliary: esophagus, stomach, duodenum, pancreas, liver, and biliary tree (except isolated cholecystectomy) (1.39)
    • Gallbladder, appendix, adrenals, spleen, biliary tree surgeries other than cholecystectomy not included (0.59)
    • Intestinal, below the level of the duodenum (1.14)
    • Neck, including thyroid and parathyroid (0.18)
    • Obstetric or gynecologic (0.76)
    • Orthopedic (0.8)
    • Abdomen, other (1.13)
    • Peripheral vascular, nonaortic, nonvein vascular surgeries (0.86)
    • Skin (0.54)
    • Spine (0.21)
    • Thoracic, except esophageal and cardiac (0.4)
    • Vein (-1.09)
    • Urology, kidneys and urinary system (-0.26)

Remember that those are not the only myocardial infarction risk factors. Still, Gupta risk score regards them as the ones with the most impact on MICA risk in patients undergoing any (non-cardiac) surgery.

How to interpret the Gupta risk calculator?

After we have the outcome of the calculation, we ought to read how it correlates to the results of 'Development and Validation of a Risk Calculator for Prediction of Cardiac Risk After Surgery', the study the Gupta risk calculator is based on. The scientists who wrote it used percentiles to demonstrate the distribution of the MICA risk among surgical patients.

Patients at a high risk of myocardial infarction or cardiac arrest present a Gupta score above 1%. They will certainly need additional cardiac evaluation after surgery.






26th - 50th


51st - 90th


91st - 95th


96th - 97th



Gupta cardiac risk calculations in practice

Let's work on an example. Caroline is a 76-year-old woman who needs a hip prosthesis. She needs some help from her carer when taking care of the house due to her severe systemic diseases. Her creatinine levels are still normal, reaching 1 mg/dL. As she has some myocardial infarction risk factors, the physician decides to estimate her overall risk of an incident during and after the surgery.

What is her MICA (Gupta cardiac risk)?

  • Age: 76 years (76)
  • Status: Partially dependent (0.65)
  • ASA: Class 3 (-1.92)
  • Creatinine 1 mg/dL (0)
  • Type of procedure: Orthopedic (0.8)

x = 0.76 * 0.02 + 0.65 + (-1.92) + 0 + 0.8 - 5.25

x= -4.2


cardiac risk [%] = e-5.7 / (1 + e-5.7)

cardiac risk [%] = 1.48 %

Her Gupta score places between 90th and 95th percentile; thus, the interpretation is that the risk of myocardial infarction or cardiac arrest after the hip prosthesis implantation surgery is high.

We try our best to make our Omni Calculators as precise and reliable as possible. However, neither we nor our content providers warrant the accuracy of the information on this site. All information on this website is for informational purposes only and is not intended to and should not serve as a substitute for medical consultation, diagnosis or treatment. Please consult your health care provider before making any health care decisions. Omni Calculator and its content providers expressly disclaim responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. Your use of the site is only your own risk.

Dominika Śmiałek, MD, PhD candidate
Totally independent
ASA Class
2: mild systemic disease
MICA score
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