EORTC Bladder Cancer Recurrence and Progression Calculator

Created by Łukasz Białek, MD
Reviewed by Dominik Czernia, PhD candidate and Jack Bowater
Based on research by
Sylvester, R. J., van der Meijden, A. P., Oosterlinck, W., Witjes, J. A., Bouffioux, C., Denis, L., Newling, D. W., Kurth, K. Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: a combined analysis of 2596 patients from seven EORTC trials European urology (March 2006)See 1 more source
Babjuk, M., Burger, M., Capoun, O., Cohen, D., Compérat, E. M., Dominguez Escrig, J. L., Gontero, P., Liedberg, F., Masson-Lecomte, A., Mostafid, A. H., Palou, J., van Rhijn, B., Rouprêt, M., Shariat, S. F., Seisen, T., Soukup, V., Sylvester, R. J. European Association of Urology Guidelines on Non-muscle-invasive Bladder Cancer (Ta, T1, and Carcinoma in Situ) European urology (January 2022)
Last updated: Aug 01, 2022

EORTC Bladder Cancer Recurrence and Progression Calculator enables you to find the probability of the recurrence and progression of a non-muscle invasive bladder cancer over one and five years. It takes into consideration six parameters concerning the medical history of the patient, and helps you to choose the appropriate treatment options.

Disclaimer: We try our best to make our Omni Calculators as precise and reliable as possible. However, this tool can never replace professional medical advice.

About bladder cancer

Bladder cancer is the most common urinary tract malignancy. It usually affects people over 60 years old and more men than women. Smoking is the biggest risk factor for developing this cancer (smoking of course causes other cancers, such as lung cancer and kidney cancer). The most typical symptom is painless hematuria (blood in the urine). Remember! If haematuria has been found, always search for bladder (or kidney) cancer!

At the time of diagnosis, around 75% of the patients have non-muscle invasive bladder cancer (NMIBC), while the remaining 25% already have an advanced disease. Patients with NMIBC generally have good survival rate, but the condition has a significant potential for recurrence of the tumor in the bladder, which may even progress into a more advanced stage of the disease.

Bladder cancer recurrence and progression probability calculator

The treatment of patients with non-muscle invasive bladder cancer should be based on their prognosis, which includes a prognosis of the tumor's recurrence and progression. This EORTC bladder cancer recurrence and progression calculator is a tool that predicts the probability of recurrence and progression and thus proposes appropriate management of patients with non-muscle invasive bladder cancer.

This calculator was built using the recommendations set out by the European Association of Urology in their guidelines on non-muscle invasive bladder cancer. This process was first described using the analysis of almost 2600 patients by Sylvester et al. in an article titled Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables. This bladder cancer prognosis calculator is a kind of scoring system which is based on six clinical and pathological factors:

  • Number of tumors;
  • Tumor size (diameter of the biggest tumor);
  • Prior bladder cancer recurrence rate;
  • Stage of the disease (T category);
  • Carcinoma in situ (in bladder cancer, CIS is always high grade, requires immediate treatment, and worsens the prognosis);
  • Tumor grade.

For each of these variables, the patient receives a score from 0 to 6 (for both the risk of recurrence and progression). The details are presented in the table:

FactorRecurrence pointsProgression points
Number of tumorssingle0
0
2-733
863
Tumor diameter<3cm00
>3cm33
Prior recurrence rateprimary00
<1 rec/year22
>1 rec/year42
StageTa00
T114
Concomitant CISNo00
Yes16
GradeG100
G210
G325
Total Score0-170-23

After calculating the recurrence points and progression points, they are transfered into percentage of risk according to the tables below:

Recurrence pointsRisk of recurrence at 1 yearRisk of recurrence at 5 years
015%31%
1-424%46%
5-938%62%
10-1761%78%
Progression pointsRisk of progression at 1 yearRisk of progression at 5 years
00.2%0.8%
2-61%6%
7-135%17%
14-2317%45%

The probabilities of recurrence and progression at one year range from 15% to 61% and from less than 1% to 17%, respectively. At the five year mark, the probabilities of recurrence and progression range from 31% to 78% and from less than 1% to 45%. By using the data attached to a specific patient, the urologist can discuss the different therapeutic options with the patient to determine which is the most appropriate treatment and what frequency of follow-up is required.

Was this calculator helpful? If you are interested in oncology check ANC calculator which helps you determine the risk of febrile neutropenia in patients undergoing chemotherapy.

Łukasz Białek, MD
Number of tumors
Select...
Tumor diameter
Select...
Prior recurrence rate
Select...
Stage of the disease
Select...
Concomitant CIS
Select...
Tumor grade
Select...
Recurrence points
Probability of recurrence at 1 year
%
Probability of recurrence at 5 years
%
Progression points
Probability of progression at 1 year
%
Probability of progression at 5 years
%
Check out 18 similar urology & nephrology calculators 🚽
Adrenal washout calculatorAlbumin creatinine ratioBladder volume… 15 more
People also viewed…

Black Hole Collision Calculator

The Black Hole Collision Calculator lets you see the effects of a black hole collision, as well as revealing some of the mysteries of black holes, come on in and enjoy!

Coffee kick

A long night of studying? Or maybe you're on a deadline? The coffee kick calculator will tell you when and how much caffeine you need to stay alert after not sleeping enough 😀☕ Check out the graph below!

RBC indices

RBC indices calculator uses hemoglobin, hematocrit, and red blood cell count values to calculate three additional parameters: MCV – mean corpuscular volume, MCH – mean corpuscular hemoglobin, and MCHC – mean corpuscular hemoglobin concentration.

Türkiye için aşı sırası hesaplayıcı

Türkiye için aşı sırası hesaplayıcı mevcut COVID aşılama stratejisine göre yaşınız, sağlık durumunuz ve işiniz gibi özellikleri baz alarak aşı sırasında nerede olduğunuzu hesaplar.
Copyright by Omni Calculator sp. z o.o.
Privacy policy & cookies
main background